|
KMID : 1128320120100010031
|
|
Electrolytes & Blood Pressure
2012 Volume.10 No. 1 p.31 ~ p.34
|
|
|
A Case of Syndrome of Inappropriate Scretion of Anti-Diuretic Hormone Associated with Sodium Valproate
|
|
Lee Hong-Joo
Wi Jung-Kook
Moon Ju-Young
Jeong Kyung-Hwan
Ihm Chun-Gyoo
Lee Sang-Hoon
Lee Tae-Won
|
|
|
Abstract
|
|
|
|
We report a rare case of the concurrent manifestation of central diabetes insipidus (CDI) and type 2 diabetes mellitus (DM). A 56 year-old man was diagnosed as a type 2 DM on the basis of hyperglycemia with polyuria and polydipsia at a local clinic two months ago and started an oral hypoglycemic medication, but resulted in no symptomatic improvement at all. Upon admission to the university hospital, the patient`s initial fasting blood sugar level was 140mg/dL, and he showed polydipsic and polyuric conditions more than 8 L urine/day. Despite the hyperglycemia controlled with metformin and diet, his symptoms persisted. Further investigations including water deprivation test confirmed the coexisting CDI of unknown origin, and the patient`s symptoms including an intense thirst were markedly improved by desmopressin nasal spray (10 μg/day). The possibility of a common origin of CDI and type 2 DM is raised in a review of the few relevant adult cases in the literature.
|
|
|
KEYWORD
|
|
|
Polyuria, Central diabetes insipidus, Type 2 diabetes mellitus : Water deprivation test
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|